Strain 19 Brucella vaccine: V. Mass production in the Brucella Vortex Aerated Culture apparatus

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Peer-Reviewed Research
  • SDG 3
  • Abstract:

    The vaccine organism Brucella abortus strain 19 has been cultured in bulk in 72 litres of liquid medium aerated in a vortex system in a stainless steel culture vessel of 250 litre capacity. The lay-out and operation of the apparatus are described and results of a series of batches produced are given. The differences between various production methods are briefly presented.