Abstract: Out of the numerous challenges facing mankind globally, the impact of climate change poses more threat. These impacts include sea-level rise, more frequent floods from heavy rainfall and notably among others, intense droughts. Despite the United Nations anchored events and conferences geared towards tackling climate change, little success has been recorded till date. Biomimicry, a novel science and method that studies nature’s models and then emulates their forms, processes, and strategies offer a sustainable approach to this menace of climate change. It also has the potential to offer efficient alternatives to the human activities that contribute to the depletion and pollution of the environment. Hence, the objective of this paper is to evaluate and present the potential of biomimicry in for climate change mitigation in the built environment. An extant literature review was conducted on biomimicry and its roles in tackling climate change through mitigation and adaptation. The result explores various Biomimetic innovations and applications with their potential to sustainably mitigate the menace of climate change if adopted. This study is expected to refocus human efforts towards biomimicry where it is believed that nature, during its 3.8 billion years of existence has evolved with highly efficient processes and systems, with the potential to produce solutions to the environmental challenges facing mankind, especially climate change.