The Senecio alkaloids Part I : the isolation of isatidine from Senecio retrorsus and Senecio isatideus

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Peer-Reviewed Research
  • SDG 12
  • SDG 3
  • Abstract:

    Isatidine has been isolated not only from S. isatideus D.C. but also from S. retrorsus D.C., not hitherto observed by other workers. S. retrorsus contains as its main alkaloid retrorsine, accompanied by isatidine in lesser quantities. S. isatideus contains as its main alkaloid isatidine, accompanied by very small quantities of retrorsine. The chemical properties of isatidine and isatinecic acid are described, as well as the hydrolysis of isatidine to isatinecic acid and the oxidation of isatidine to oxalic acid. The pharmacology, pathology and further structural results with isatidine will be reported