Efficient radiosynthesis of a [18F]-phosphonium salt containing closo-carborane

20 December 2019

An efficient synthesis of an 18F-labelled phosphonium salt containing closo-carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for the latter. An X-ray structure for the unlabelled 19F salt is also presented.